2011年3月11日

PDE5 inhibitor therapy on three major issues.


PDE5 inhibitors currently in use were very irregular, and standardized use of PDE5 inhibitors is the key to cure the disease.The use of PDE5 inhibitor currently mainly in the following three questions:.
1.       Medication method is not correct.Studies have shown that medication errors accounted for 81% of patients, mainly high-fat foods in the consumption of medication, medication immediately after sex, not the effectiveness of stimulation, or simply conducted a number of attempts.Available information indicates that high-fat diet can reduce the rate of drug absorption, so that the maximum plasma concentration increased by about 1 hour of time, while the average maximum plasma concentration decreased by 18%.
Under normal circumstances, the three PDE5 inhibitor class of drugs vary the onset time, Viagra was 0.8 to 1 hour, 2 hours tadalafil, vardenafil was 0.9 hours, so that patients immediately after taking the sex life or simply follow the medication half an hour before sex, the result may not be ideal.Also be pointed out that, PDE5 inhibitors do not produce an effect on the central nervous system and can not increase sexual desire, there must be sufficient medication to the onset of sexual stimulation.
2.       Does not meet the effective treatment dose.Including a single oral dose did not achieve an effective dose and effective treatment, not adhere to the medication.ED treatment only in the repeated use of drugs in order to improve and consolidate the efficacy of intermittent treatment is difficult to achieve satisfactory results.And in clinical drug choice, there are some great doctors arbitrary, and thus is not clear which drugs the patient the most suitable for them, leading to irregular medication, dose and unstable situation.
3.       Does not adhere to medication treatment.A study found that more than 3 years, 57% of patients stop treatment.Japan in the analysis of 667 patients after successful treatment for the first time that the 3-year follow-up period, there is 48% of patients the treatment is interrupted.Clinical experts, ED patients should adhere to long-term medication, immobilization, not only in the sexual use.
Faced with many patients rely on drugs can not cure ED concerns, ED can be cured.Proportion of patients through medication ED, build confidence in the future when the drug dose can be gradually reduced to finally can not take medication can be turned into complete normal sexual life.

没有评论:

发表评论