How the diabetes cause ED? Talk from four angle

How the diabetes cause ED? Talk from four angle   

Generally think erectile nerve is affected by pelvic viscera nerve and nerve domination, these pussy sacral nerve originated in the vertebral (S2 ~ S4) in the plane of the spinal cord, when patients with diabetes mellitus neural pathological changes involving these neural occurs when impotence. Recent research data show that the incidence of diabetes impotence with course and severity is closely related, namely, the longer the duration of diabetes, the more serious illness, the higher incidence of impotence. These impotence patients with 84% exist other nerve damage, and diabetes mellitus not performance, less than in patients with impotence 12% of patients with other nerve damage.

Another according to relevant material report: diabetic patients with bladder the impotence of disorders often associated with bladder, because penile erectile function by the same nerve and spinal cord central control. Someone with diabetes of impotence on bladder pressure determination, the results indicated that 80% visible abnormalities.

Diabetic neuropathy triggered impotence, the exact cause is still unclear, it is generally thought that there are several theories:

(1) metabolic disorders doctrine: diabetes because of the relative or absolute insulin secretion in shortage, and accompanied by the stress of too much in the circulation of blood glucose discomfort factor is increased and lipid metabolism local change accordingly foundation, due to glucose activation obstacles and lipid metabolic disorders, peripheral nerve absorb glucose decrease, nerve fructose, sorbitol increase due to increased, cells osmotic pressure caused dysfunction. Not control diabetes, lipid metabolism disorder, coenzyme A necessary vinegar acetylation in low sulfur kinase diabetes, membrane formation obstacles, accompanied by A demyelinated and cell degeneration of ganglion section damage. These ill caustic usually feel whole body, motor-neuron, nerve root, spinal cord and the autonomic nervous system.

(2) vascular disorders doctrine: diabetes is the most common chronic complications of diabetes vascular complications, also is the main threat to the death, disability. Diabetes can make the hyperglycemia blood-clotting heighten, red deformation property is abate, platelet clumping function abnormal increase. In capillary pathological changes, there are high perfusion, high filtration, etc, microcirculation, dynamic change oxygen, the basement membrane thickening and composition change involved. In addition, vascular endothelial injury theory is the hot topic research in recent years, � PGI front row ring hormone (2) after the endothelial synthesis released into the body blood concentration in diabetic patients, reduced significantly, and weaken the vessels to dilate and platelet anticoagulation role, fibrinolysis enzymes from the vascular endothelial activation factor releases quantity reduce blood clotting, increases the sexual heighten. Because blood stream is slow, blood capillary basement membrane thickening, ischemia heavier.

Insulin is diabetes metabolic disorder is one of the important factors vascular disorders. Diabetes insulin secretion relative shortage and absolute lack of. Insulin overmuch can stimulate arterial smooth muscle hyperplasia, strengthen cholesterol and fat synthesis and deposition in blood vessel walls. Insulin is less and less, because of lipoprotein cleared after hematic disease caused by high lipoprotein. So too are less insulin can cause atherosclerosis.

(3) vitamin deficiency: someone found diabetes patients reduce vitamin B clan concentration. Vitamin B participate in various metabolic body was put forward for people with diabetes should long-term supplement vitamin B clan.

(4) stress theories: diabetes is caused by environmental factor interactions a syndrome. Stress can make the diabetes increase or worse. Due to the stress in the hypothalamus, the brain cortex of neuropeptide active strengthening, between sugar metabolism, caused lipid metabolism, endocrine dysfunction, make the abnormal further deterioration of peripheral nerve.