2011年3月11日

ED treatment should vary


Male ED (erectile dysfunction) in patients receiving treatment, they often also face the problem how to choose the treatment options.To the professional specialist hospital for medical treatment, the treatment should be preceded by the necessary checks accepted, then the treatment should be individualized, may well be the best treatment.
Currently the treatment of ED are: oral drugs such as PDE-5 inhibitor; vacuum suction; intracavernous injection of vasoactive drugs; hormone therapy; surgical treatment, and dietary and lifestyle changes and so on.These methods, oral medication because of its efficient, safe, convenient and other advantages, was 2010, the European Urological Association guidelines recommend for the treatment of ED treatment of choice.
ED drugs commonly used oral PDE-5 inhibitor (phosphodiesterase type 5 inhibitor), is the WHO-recommended first-line treatment of ED drugs in clinical use for more than 10 years.Clinically, there are three such drugs: tadalafil (Cialis), sildenafil (Viagra), vardenafil (Levitra), three are prescription drugs, so doctors need guidance in use.Role of the principle that they are expanding the penis through blood vessels, increase blood flow, thereby restoring normal erectile function well.
According to the different duration of drug action, these drugs have long-term and short-acting of the points.Short-acting preparations to sildenafil, represented about 4 hours when the drug because of efficacy by high-fat diet and the influence of alcohol, it is required to take to avoid these disturbances.Another long-acting agent to represented tadalafil, the role of time is 36 hours, the patients and partners can be any time within 36 hours, select the appropriate time for married life, and from high-fat diet and alcohol impact.
The choice of drug, in principle, according to the actual needs of patients or recommend, such as the number of their sexual life and their own expectations on the treatment goals, and the clinical experience of doctors to decide to use short-acting or long-term.Short-acting agents that hope is more suitable for a short time of life, relatively rigid, or the law of sexual partners, long-acting formulations are more suitable for those who like arbitrary, relatively no fixed time for sex, or the relatively high demand for sex partner.Typically, ED patients in the treatment of early, prolonged lack of satisfactory performance, often feel nervous, and relatively long period of time so they have more fully prepared for a more relaxed attitude, sex life will seem more natural satisfaction.
To be re-emphasized that, ED treatment of oral drugs for prescription drugs, must receive formal treatment of the premise, with its own needs and follow medical advice to take.Are taking any form of nitrates for patients must not use PDE-5 inhibitor, as PDE-5 inhibitor combination with nitrates will lead to sharp decline in blood pressure, cardiac risk of hypoxia.In addition, cardiovascular diseases such as myocardial infarction, angina pectoris and the prescription of PDE-5 inhibitor and its components in allergic patients can not use PDE-5 inhibitors.

ED treatment should be standardized

According to WHO guidelines, FDE5 inhibitors are first-line treatment of ED drugs, but despite the fast FDE5 inhibitor effects, side effects, there are still many patients refuse to use FDE5 inhibitors, because of the high price of such products, time is short.PDE5 inhibitor for the treatment of a new generation of ED provides a new therapeutic approach.
Currently there are three PDE5 inhibitors: sildenafil, vardenafil, tadalafil.Pharmacokinetics showed that the highest concentration of sildenafil up to 560ng/ml, the highest for the three drugs; sildenafil and vardenafil as 4 hours after taking the drug can be excreted, there is expected taken as early as possible before having sex (0.5 to 4 hours may be); Sildenafil and vardenafil are affected by the high-fat diet to slow absorption, but bioavailability varies widely between the two were 40% and 15%, indicating that the bioavailability of vardenafil low; tadalafil role in the body to maintain up to 24 ~ 36 hours, excreted slowly, and can accumulate in the body for long-acting preparations.
From the perspective of pharmacokinetics, bioavailability may result difficult to predict the low rate of drug dosage required, the effective blood concentration variation and increased risk of drug interactions.Thus, while sildenafil and tadalafil is more appropriate for ED patients, but because of the short efficacy of sildenafil, ED is not conducive to healing.
64% of middle-aged ED patients have chronic diseases such as cardiovascular disease, diabetes and so on.In the United States of MONMENTUS study, through a multi-center study in the ED evaluation of tadalafil in men with multiple complications, the efficacy and safety of the 155 cases of patients suffering from complications of treatment for 12 weeks and found taking tadalafil most common adverse events were headache (5.9%), hot flashes (3.9%), nasal congestion (3.2%), only 3% of patients discontinued because of adverse events and no patients taking tadalafil as The complications of the original impact, or increase the previous complications.

Drink less!Careful impotence!

Too much alcohol this substance into the human body, will cause the body to produce a series of adverse reactions, but also caused the decline of sexual even cause of erectile dysfunction (English abbreviation for the ED).So what is the alcohol content of what causes ED?May as well make some of the following areas:
The first is the impact on the nervous system:
A transient excited about drinking the cerebral cortex, "Command", but it will turn into restrained.If the excited state in this short period of sexual intercourse under the rush will be too excited, reckless and rude, even gaffe prone to sexual deviation, it tends to provoke accusations of spouses, often as a result of poor psychological state of ED caused by laying the seeds.If the inhibition by the excitement into sexual intercourse, due to the control capabilities of the nervous system in the inhibitory state, ED and the even more reasonable.
Followed by the vascular system:
Just drink, people will feel bursts of fever, facial flush thrown, because this time the blood concentration of a large number of blood vessels inside the brain and skin, and if time sex, sex organs suddenly need a lot of blood, there will be in short supply, how the penis it can be a good erection?Flush with the face when the fever subsided, a large number of blood deposition in visceral organs, people actually feel cold, so when you have sexual intercourse, sexual organs the blood supply is still not ideal, but will occur ED.
The third is the sex hormone metabolism:
After drinking large amounts of blood in the amount of male hormone testosterone will be reduced.This is because alcohol prevents testicular production of testosterone directly, but on the other hand the stimulation of alcohol, the liver will speed up the processing of testosterone, a lot of testosterone is broken down into other substances conveyed.Moreover, long-term drinkers will inevitably occur to some extent in alcoholic liver cirrhosis, although the processing power of testosterone will be weakened, the result increased estrogen levels, in short, testosterone or estrogen to reduce the increase, can cause erectile dysfunction obstacles.
Finally, the impact on the overall physical condition:
Long-term drinking or frequent drunken man, and will show weight loss, fatigue, loss of appetite, particularly in the gastrointestinal mucosa to stimulate alcohol content, it will seriously hamper the digestive function, causing decreased levels of nutrition, so the overall physical deterioration, also with sexual The decline, if there is erectile dysfunction, is not surprising.

Does masturbation lead to impotence



Masturbation is a normal phenomenon, masturbation is not the appropriate impact on the body, but if excessive masturbation can lead to impotence, premature ejaculation and other Nankejibing.
how to understand this phenomenon of Masturbation ?
In general, for unmarried young people in terms of masturbation is a normal phenomenon, generally once a week or so will not affect health.But if too frequent masturbation, then there is likely to affect their health, and may cause urinary and reproductive system infections such as chronic prostatitis, impotence, premature ejaculation, in concentrating, memory loss, poor sleep and other symptoms.
Masturbation refers to sexual organs by hand or other objects to achieve orgasm fondle behavior, 90% of men and 30% of women have had the phenomenon of masturbation, male masturbation in the early age of 18, can cause genital hypoplasia, renal early recession, the long-term masturbation can cause penile curvature, short, impotence, premature ejaculation.The number of adolescent masturbation should be controlled in the following 2 times a month is appropriate, female masturbation should avoid using hard objects into the vagina, so as not to cause damage and a variety of vaginal inflammation.
Frequent masturbation impotence it?Regular masturbation hazards.
Masturbation itself does not cause any harm and adverse consequences.If frequent masturbation, a habit, and even that masturbation can replace the sexual life, masturbation and then create a mental burden and difficult to extricate themselves, especially those who happen masturbation, will produce psychological guilt and remorse, often want to correct, but in the physiological spontaneous impulse and is difficult to self-control, from the good wishes and a setback, leading to mental impairment.And excessive masturbation can cause a number of urinary and reproductive system diseases, sexual neurasthenia.
Many men masturbate before marriage has a long history of marriage will have to worry about impotence, of married life, in fact, masturbation is not necessarily associated with erectile dysfunction, many worry that it is not necessary, contrary to some extent appropriate sexual masturbation promoted the increase.However, if excessive masturbation can lead to the occurrence of impotence.
Male friends in their daily lives to develop good habits, try to avoid the occurrence of impotence.Once symptoms appeared impotence, must be timely to professional norms of treatment institution for medical treatment, so as not to delay treatment.